Keys Disease Charters

5.0/5 (36 reviews)

Recent reports

Federally permitted

Overseas Highway 33000, Big Pine Key, FL 33043, United States–

Keys Disease Charters

Federally permitted

5.0/5 (36 reviews)

Overseas Highway 33000

Big Pine Key, FL, United States

Trips & prices Targeted species Boat info What's biting What's included Contact captain

Trips & prices What's included Targeted species Boat info Reviews Contact captain

Winter fishing in the florida keys offers some of the best fishing there is to offer. Sailfish, wahoo, tuna, cobia, mackerel, snapper, grouper and mahi will push through the keys waters as the water temperature drops. We offer high-speed trolling trips, live bait bump trolling, reef fishing, deep drop, wreck fishing, bridge fishing and bay fishing. The choice is yours and captain will let you know what has been the successful bite prior to the trip.

Families who love fishing together will be glad to know that kids are welcome aboard! Child life jackets are available. Customers are encouraged to bring sunscreen, sunglasses, snacks and drinks. An iced down, large yeti cooler will be provided along with waters for anything you would like to keep cool.

Your vessel for the day is a 27' Century center console powered by a 350 mercury verado with room for 4 passengers. It is loaded with all of the appropriate gear to put some large fish in the boat. Also lined with new seadek for extra cinfortable fishing. You'll find rods, reels, and tackle waiting for you, along with lures. Live bait will be in the live well at pick up if available but some live bait will caught during the trip.

There's no need to buy a fishing license, just show up ready for a good time! Keep in mind that some fish may have harvest limits or closed seasons. If you don't know what to expect, ask the captain.

Go ahead and treat yourself to a day on the water with Keys Disease Charters.

Rating

5.0

36 reviews

4.9

Boat & equipment

5.0

Captain & crew

5.0

Fishing Experience

Anglers' gallery (109)

Two anglers proudly displaying a large Sailfish aboard their boat during a deep-sea fishing trip.

Young angler proudly holding a large Snapper while fishing on a boat, showcasing a successful catch in a vibrant marine environment.

+103

What anglers say

97%

Recommended

100%

Caught fish

All reviews (36)

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Showing 1 – 5 of 36 reviews

Matt Thede

Miami, Florida

5.0

Awesome Trip with Captain Chris!

4 hr (PM) on January 10, 2026

From the very start of the trip, Chris was great with communication and setting up our group to be successful. I had six high school students who wanted to fish with two adults, so he was absolutely fantastic and making sure we had a great experience. He spent his morning catching us bait so that when we arrived for our 1 o'clock arrival time, we were already set up for success. When on the boat, he was friendly, personal, and related with all of us. He made sure that we had everything we needed when we needed it. At the first location, we ended up catching some mackerel and snapper for supper, and then headed out to deeper Waters to try for some tuna and sailfish. He put us in the right spot and it wasn't long before the tuna were boiling at the surface and we had multiple fish on at one time. He did not get frustrated at us when our fishing skills were lacking. Instead, he instructed us and helped us with the next hook set, helping us be successful....which translated into a bunch of happy customers! I cannot recommend him enough if you are in the Marathon area or Big Pine Key area. Will definitely be looking him up again when we come back!

Reported catch:

Response from Captain

January 13, 2026

thanks for the review, Matt and thanks for choosing keys disease charters. Had a blast fishing with you guys and hope to see you guys back soon 🎣

Stuart Trueax

5.0

Verified

New

Fishing on the Gulf.

4 Hour (AM) on March 6, 2026 • 3 adults

Chris took me and my two grandsons out for 4 hour fishing on the Gulf. We immediately started catching fish within two minutes of casting our lines. We even caught an 8' Lemon Shark, quite an experience reeling it in as it would weigh around 250 lbs. We caught a Sea Trout which we grilled for dinner that evening. 😋 Chris did a great job, we all had fun and would love to do it again.

Angler proudly displaying a large Grouper while fishing on a boat in clear blue waters.

A shark swimming in clear blue waters, captured from above, showcasing the marine environment.

Reported catch:

Response from Captain

March 7, 2026

Thanks for the review stuart! Had a blast catching fish witb you and your grandsons. thanks for choosing Keys Disease Charters.

Aaron Lorentz

5.0

Verified

Excellent Day…we’ll be back!

6 Hour reef/wreck on January 2, 2026 • 2 adults

My son (16) and I had a great day on the water with Captain Chris. My son wanted to get on tarpon. Although it wasnt the greatest time of year dor tarpon, TARPON ON! Unfortunately they threw the hook but we witnessed some amazing aerials and got some great video. After a few hours, Captain Chris took us out to a wreck and we werw constantly on fish - Blue Runners, Jack Crevalle, Baracuda, and a Goliath Grouper. It was a great adventure and we’ll definitely be back! Thank you, Captain Chris!

Reported catch:

Response from Captain

January 11, 2026

thanks for the review aaron and thanks for choosing keys disease charters! we look forward to having you back on the water soon 🎣

Amanda Kelly

5.0

Verified

Beyond our expectations!

4 Hour (AM) on January 29, 2026 • 3 adults

Chris was very easygoing that it didnt even feel like we were out with a unknown guide, but just out having fun with a friend. He was very attentive and educational. This was our first time doing a fishing trip and we are now hooked. Our 13yr old made lifetime memories fighting in a 34inch Goliath grouper and a bull shark! Chris prepared our keeps so we got to leave with a great dinner for the evening! Beyond 5 stars and highly reccomend!! You won't regret it!!

Reported catch:

Abigail Alibozek

5.0

Verified

New

Great time fishing

2 hr sunset cruise/sightseeing on March 19, 2026 • 2 adults

We had a great time catching multiple species of fish. Weather was a little difficult but the Captain made it workout. He was informative of fish species and their seasons / size requirements.

Response from Captain

March 20, 2026

Thank you so much for the review! I had a great time fishing with you guys today and hope to see you guys in the future!

Trip availability and prices

Trip Date:

Days:

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March 2026

Su	Mo	Tu	We	Th	Fr	Sa

Number of days

Group Size

2 adults • 0 children

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Almost there...

2 hr sunset cruise/sightseeing - 4:00 PM

FREE Cancellation 3 days notice

2 Hour Trip

starts at 4:00 PM

US $500