Keys Disease Charters 

5.0/5 (46 reviews)
Recent reports
 
Federally permitted
 Overseas Highway 33000, Big Pine Key, FL 33043, United States

Keys Disease Charters 

Federally permitted
Big Pine Key, FL, United States
27 ft
4
5.0/5 (46 reviews)

Winter fishing in the florida keys offers some of the best fishing there is to offer. Sailfish, wahoo, tuna, cobia, mackerel, snapper, grouper and mahi will push through the keys waters as the water temperature drops. We offer high-speed trolling trips, live bait bump trolling, reef fishing, deep drop, wreck fishing, bridge fishing and bay fishing. The choice is yours and captain will let you know what has been the successful bite prior to the trip.

Families who love fishing together will be glad to know that kids are welcome aboard! Child life jackets are available. Customers are encouraged to bring sunscreen, sunglasses, snacks and drinks. An iced down, large yeti cooler will be provided along with waters for anything you would like to keep cool.

Your vessel for the day is a 27' Century center console powered by a 350 mercury verado with room for 4 passengers. It is loaded with all of the appropriate gear to put some large fish in the boat. Also lined with new seadek for extra cinfortable fishing. You'll find rods, reels, and tackle waiting for you, along with lures. Live bait will be in the live well at pick up if available but some live bait will caught during the trip.

There's no need to buy a fishing license, just show up ready for a good time! Keep in mind that some fish may have harvest limits or closed seasons. If you don't know what to expect, ask the captain.

Go ahead and treat yourself to a day on the water with Keys Disease Charters.

Winter fishing in the florida keys offers some of the best fishing there is to offer. Sailfish, wahoo, tuna, cobia, mackerel, snapper, grouper and mahi will push through the keys waters as the water temperature drops. We offer high-speed trolling trips, live bait bump trolling, reef fishing, deep drop, wreck fishing, bridge fishing and bay fishing. The choice is yours and captain will let you know what has been the successful bite prior to the trip.

Families who love fishing together will be glad to know that kids are welcome aboard! Child life jackets are available. Customers are encouraged to bring sunscreen, sunglasses, snacks and drinks. An iced down, large yeti cooler will be provided along with waters for anything you would like to keep cool.

Your vessel for the day is a 27' Century center console powered by a 350 mercury verado with room for 4 passengers. It is loaded with all of the appropriate gear to put some large fish in the boat. Also lined with new seadek for extra cinfortable fishing. You'll find rods, reels, and tackle waiting for you, along with lures. Live bait will be in the live well at pick up if available but some live bait will caught during the trip.

There's no need to buy a fishing license, just show up ready for a good time! Keep in mind that some fish may have harvest limits or closed seasons. If you don't know what to expect, ask the captain.

Go ahead and treat yourself to a day on the water with Keys Disease Charters.

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Customer reviews

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Rating

5.0
46 reviews
5.0
Boat & equipment
5.0
Captain & crew
5.0
Fishing Experience

Anglers' gallery (153)

What anglers say

100%
Great experience
97%
Family friendly
100%
Friendly captain
100%
Good boat
98%
Recommended
100%
Caught fish

All reviews (46)

Frequently mentioned
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Showing 15 of 46 reviews
Jonathan Winn
Jonathan Winn
us
Paragould, AR, US
Member since 2026
5.0
Verified
Great Trip!!! Couldn’t ask for any better !!!
6 Hour reef/wreck on May 16, 20262 adults

What a fishing trip!!! Just like we had dreamed about. My son wanted to catch a huge Mahi Mahi (Dolphin) and that’s exactly what happened. Captain Chris explained how the fishing trip would go and what signs on the water we would be looking for. Within the first hour of searching for signs of Mahi Mahi we landed a huge 54 inch Bull. It took 17 minutes to reel in and Captain Chris guided my son the whole way. It was the experience of a lifetime and it didn’t end there!!! We ended up catching a huge nurse shark, many yellowtail snapper, a couple remora and another I can’t remember the name of.

Reported catch:
Dolphin (Mahi Mahi)
Yellowtail Snapper
Response from Captain

Thank you for the review, Jon and thanks for choosing Keys Disease Charters. it was a blast fishing with you and your son. Hope to see you guys back in the future 🎣

Matt Thede
Matt Thede
Member since 2026
5.0
Awesome Trip with Captain Chris!
4 hr (PM) on January 10, 2026

From the very start of the trip, Chris was great with communication and setting up our group to be successful. I had six high school students who wanted to fish with two adults, so he was absolutely fantastic and making sure we had a great experience. He spent his morning catching us bait so that when we arrived for our 1 o'clock arrival time, we were already set up for success. When on the boat, he was friendly, personal, and related with all of us. He made sure that we had everything we needed when we needed it. At the first location, we ended up catching some mackerel and snapper for supper, and then headed out to deeper Waters to try for some tuna and sailfish. He put us in the right spot and it wasn't long before the tuna were boiling at the surface and we had multiple fish on at one time. He did not get frustrated at us when our fishing skills were lacking. Instead, he instructed us and helped us with the next hook set, helping us be successful....which translated into a bunch of happy customers! I cannot recommend him enough if you are in the Marathon area or Big Pine Key area. Will definitely be looking him up again when we come back!

Reported catch:
Yellowtail Snapper
Blackfin Tuna
Response from Captain

thanks for the review, Matt and thanks for choosing keys disease charters. Had a blast fishing with you guys and hope to see you guys back soon 🎣

Aaron Lorentz
Aaron Lorentz
Repeat angler
us
Ohio, US
Member since 2022
6 trips
5.0
Verified
Excellent Day…we’ll be back!
6 Hour reef/wreck on January 2, 20262 adults

My son (16) and I had a great day on the water with Captain Chris. My son wanted to get on tarpon. Although it wasnt the greatest time of year dor tarpon, TARPON ON! Unfortunately they threw the hook but we witnessed some amazing aerials and got some great video. After a few hours, Captain Chris took us out to a wreck and we werw constantly on fish - Blue Runners, Jack Crevalle, Baracuda, and a Goliath Grouper. It was a great adventure and we’ll definitely be back! Thank you, Captain Chris!

Reported catch:
Goliath Grouper
Tarpon
Response from Captain

thanks for the review aaron and thanks for choosing keys disease charters! we look forward to having you back on the water soon 🎣

Amanda Kelly
Amanda Kelly
us
Pennsylvania, US
Member since 2025
5.0
Verified
Beyond our expectations!
4 Hour (AM) inshore/reef on January 29, 20263 adults

Chris was very easygoing that it didnt even feel like we were out with a unknown guide, but just out having fun with a friend. He was very attentive and educational. This was our first time doing a fishing trip and we are now hooked. Our 13yr old made lifetime memories fighting in a 34inch Goliath grouper and a bull shark! Chris prepared our keeps so we got to leave with a great dinner for the evening! Beyond 5 stars and highly reccomend!! You won't regret it!!

Reported catch:
Goliath Grouper
Yellowtail Snapper
William Vernier
William Vernier
Repeat angler
us
Michigan, US
Member since 2019
2 trips
5.0
Verified
Great Charter!
6 hr bridge/inshore on May 14, 20262 adults

Captain Chris was great. He asked us what we wanted to fish for right off the batt and then he took us to rhe fish. The boat was nice and spacious and handles the inland and off shore waves well. I wanted big fish and that is what I cought. Got two goliath grouper and two sharks! Chris was very easy to talk with and answered all the questions we had. Was a very fun day on the water. Highly recommend the 6hr trip.

Reported catch:
Goliath Grouper
Mutton Snapper
Yellowtail Snapper
Response from Captain

thanks for the review william and thanks for choosing Keys Disease Charters. had a blast fishing with you and your wife and would love to have you back in the future 🎣

Trip availability and prices

Trip Date:
Group Size:
Select date to see availability
June 2026
SuMoTuWeThFrSa
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Number of days
1
Group Size
2 adults • 0 children
Change
Almost there...
4 Hour (AM) inshore/reef
4 hour trip starts at 8:00 AM
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US $700
Entire boat: up to 4 people
4 hr (PM)
4 hour trip starts at 1:00 PM
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US $750
Entire boat: up to 4 people
5 hr (am)
5 hour trip starts at 8:00 AM
Seasonal trip
May 1 - Sep 15
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US $800
Entire boat: up to 4 people
6 hr bridge/inshore
6 hour trip starts at 8:00 AM
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US $800
Entire boat: up to 4 people
6 Hour reef/wreck
6 hour trip starts at 8:00 AM
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US $900
Entire boat: up to 4 people
6 hr mahi-mahi
6 hour trip starts at 8:00 AM
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US $1,000
Entire boat: up to 4 people
8 Hour reef/wreck
8 hour trip starts at 7:30 AM
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US $1,100
Entire boat: up to 4 people
8 hour deep sea (mahi-mahi)
8 hour trip starts at 8:00 AM
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US $1,300
Entire boat: up to 4 people
There are 11 people looking at this charter.

Customer reviews

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Rating

5.0
46 reviews
5.0
Boat & equipment
5.0
Captain & crew
5.0
Fishing Experience

Anglers' gallery (153)

What anglers say

100%
Great experience
97%
Family friendly
100%
Friendly captain
100%
Good boat
98%
Recommended
100%
Caught fish

All reviews (46)

Frequently mentioned
Loading...Loading...Loading...Loading...Loading...Loading...Loading...Loading...
Showing 15 of 46 reviews
Jonathan Winn
Jonathan Winn
us
Paragould, AR, US
Member since 2026
5.0
Verified
Great Trip!!! Couldn’t ask for any better !!!
6 Hour reef/wreck on May 16, 20262 adults

What a fishing trip!!! Just like we had dreamed about. My son wanted to catch a huge Mahi Mahi (Dolphin) and that’s exactly what happened. Captain Chris explained how the fishing trip would go and what signs on the water we would be looking for. Within the first hour of searching for signs of Mahi Mahi we landed a huge 54 inch Bull. It took 17 minutes to reel in and Captain Chris guided my son the whole way. It was the experience of a lifetime and it didn’t end there!!! We ended up catching a huge nurse shark, many yellowtail snapper, a couple remora and another I can’t remember the name of.

Reported catch:
Dolphin (Mahi Mahi)
Yellowtail Snapper
Response from Captain

Thank you for the review, Jon and thanks for choosing Keys Disease Charters. it was a blast fishing with you and your son. Hope to see you guys back in the future 🎣

Matt Thede
Matt Thede
Member since 2026
5.0
Awesome Trip with Captain Chris!
4 hr (PM) on January 10, 2026

From the very start of the trip, Chris was great with communication and setting up our group to be successful. I had six high school students who wanted to fish with two adults, so he was absolutely fantastic and making sure we had a great experience. He spent his morning catching us bait so that when we arrived for our 1 o'clock arrival time, we were already set up for success. When on the boat, he was friendly, personal, and related with all of us. He made sure that we had everything we needed when we needed it. At the first location, we ended up catching some mackerel and snapper for supper, and then headed out to deeper Waters to try for some tuna and sailfish. He put us in the right spot and it wasn't long before the tuna were boiling at the surface and we had multiple fish on at one time. He did not get frustrated at us when our fishing skills were lacking. Instead, he instructed us and helped us with the next hook set, helping us be successful....which translated into a bunch of happy customers! I cannot recommend him enough if you are in the Marathon area or Big Pine Key area. Will definitely be looking him up again when we come back!

Reported catch:
Yellowtail Snapper
Blackfin Tuna
Response from Captain

thanks for the review, Matt and thanks for choosing keys disease charters. Had a blast fishing with you guys and hope to see you guys back soon 🎣

Aaron Lorentz
Aaron Lorentz
Repeat angler
us
Ohio, US
Member since 2022
6 trips
5.0
Verified
Excellent Day…we’ll be back!
6 Hour reef/wreck on January 2, 20262 adults

My son (16) and I had a great day on the water with Captain Chris. My son wanted to get on tarpon. Although it wasnt the greatest time of year dor tarpon, TARPON ON! Unfortunately they threw the hook but we witnessed some amazing aerials and got some great video. After a few hours, Captain Chris took us out to a wreck and we werw constantly on fish - Blue Runners, Jack Crevalle, Baracuda, and a Goliath Grouper. It was a great adventure and we’ll definitely be back! Thank you, Captain Chris!

Reported catch:
Goliath Grouper
Tarpon
Response from Captain

thanks for the review aaron and thanks for choosing keys disease charters! we look forward to having you back on the water soon 🎣

Amanda Kelly
Amanda Kelly
us
Pennsylvania, US
Member since 2025
5.0
Verified
Beyond our expectations!
4 Hour (AM) inshore/reef on January 29, 20263 adults

Chris was very easygoing that it didnt even feel like we were out with a unknown guide, but just out having fun with a friend. He was very attentive and educational. This was our first time doing a fishing trip and we are now hooked. Our 13yr old made lifetime memories fighting in a 34inch Goliath grouper and a bull shark! Chris prepared our keeps so we got to leave with a great dinner for the evening! Beyond 5 stars and highly reccomend!! You won't regret it!!

Reported catch:
Goliath Grouper
Yellowtail Snapper
William Vernier
William Vernier
Repeat angler
us
Michigan, US
Member since 2019
2 trips
5.0
Verified
Great Charter!
6 hr bridge/inshore on May 14, 20262 adults

Captain Chris was great. He asked us what we wanted to fish for right off the batt and then he took us to rhe fish. The boat was nice and spacious and handles the inland and off shore waves well. I wanted big fish and that is what I cought. Got two goliath grouper and two sharks! Chris was very easy to talk with and answered all the questions we had. Was a very fun day on the water. Highly recommend the 6hr trip.

Reported catch:
Goliath Grouper
Mutton Snapper
Yellowtail Snapper
Response from Captain

thanks for the review william and thanks for choosing Keys Disease Charters. had a blast fishing with you and your wife and would love to have you back in the future 🎣

FAQs about Keys Disease Charters

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The fish you can target

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What is the boat like?

Boat image
Boat category
Center console boats
Capacity
4 persons
Boat length
27 ft
Year built
1996
Restored in
2023
Boat manufacturer
Century
Boat type
Center console
Engine model
Mercury
Powered by
1 x 350HP
Max cruising speed
40 knots
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What’s biting in Big Pine Key right now

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Recent fishing reports


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